Historical chemical annotations of Cinchona bark collections are comparable to results from current-day high‑pressure liquid chromatography technologies.
We found the content of quinine-like alkaloids from historical Cinchona barks were stable over time by comparing historical chemical annotations to HPLC estimations.
Nataly Allasi Canales, Tobias Nikolaj Gress Hansen, Claus Cornett, Kim Walker, Felix Driver, Alexandre Antonelli, Carla Maldonado, Mark Nesbitt, Christopher J. Barnes, Nina Rønsted. Journal of Ethnopharmacology. 2020. https://doi.org/10.1016/j.jep.2019.112375